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Sharon Yvette Angelina M. Villanueva, MMSc., PhD, DPAM
Associate Professor IV

Dr. Villanueva finished her BS Public Health degree from the College of Public Health in 1997 and later on took up her Master of Medical Science degree from the Graduate School of Medical Sciences, Kyushu University. In 2010, she also finished her PhD in Medical Sciences with a specialty on Pathological Sciences from the same institution. Dr. Villanueva is also a Post-doctoral fellow of the JST-JICA Agency (Japan Science and Technology Agency-Japan International Cooperation Agency) in partnership with Kyushu University and Chiba Institute of Science.

Dr. Villanueva has 21 international publications with focus on Leptospirosis seroprevalence, pathogenesis, serologic and molecular diagnosis and vaccine production.



  • Masuzawa T, Sakakibara K, Saito M, Hidaka Y, Villanueva SYAM, Yanagihara Y, Yoshida S (2018). Characterization of Leptospira species isolated from soil collected in Japan. Microbiology and Immunology. (2018); 62 (1); 55-59
  • Saito M, Villanueva SY, Masuzawa T, Haraguchi Y, Ita S, Miyahara S, Ozuru R, Yamaguchi T, Yoshimura M, Ikejiri M, Aramaki N, Amran MY, Muslich LT, Iida K, Yanagihara Y, Gloriani NG, Yoshida S.. The usefulness of semi-soild medium in the isolation of highly virulent Leptospira strains from wild rats in an urban area of Fukuoka, Japan. Doi:10.1111/1348-0421.12260.PMID:25890990. Microbiol. Immunol. (2015); 59(6); 322-30
  • Gloriani NG, Cavinta LC, Roxas EA, Villanueva SYAM. Prevention and Control of Leptospirosis in the Philippines: A Manual for Health Workers.. DOST-PCHRD. (2015); ;
  • Tatsuma A, Mitsumasa S, Villanueva SYAM, Takaaki K, Gloriani NG, and Yoshida S.. Natural defense by saliva and mucosa against oral infection by Leptospira.Can. J. Microbiol.. . (2014); ;
  • Takaya S, Nomura KH, Villanueva SYAM, Saito M, Nomura K, Gloriani NG, Yoshida S.. Identification of leptospiral 3-hydroxyacylCoA dehydrogenase released in the urine of infected hamsters.. BMC Microbiology 2014. (2014); 14; 132
  • Villanueva SYAM, Saito M, Baterna RA, Estrada CAM, Rivera AKB, Dato MC, Zamora PRF, Segawa T, Cavinta LL, Fukui T, Masuzawa T, Yanagihara Y, Gloriani NG, Yoshida S. . Leptospirarat-human relationship in Luzon, Philippines. Microbes and Infection xx . 1e9 (2014); ;
  • Villanueva, S.Y.A.M., Saito, M., Baterna, R.A., Estrada, C.A.M., Rivera, A.K.B., Dato, M.C., ... & Yoshida, S.I. . Leptospira-rat-human relationship in Luzon, Philippines. Microbes and Infection. (2014); 16 (11); 902-910
  • Villanueva SYAM, Saito M, Tsutsumi Y, Segawa T, Baterna RA, Chakraborty A, Asoh T, Miyahara S, Yanagihara Y, Cavinta LL, Gloriani NG, Yoshida S. . High virulence in hamsters of four dominant Leptospira serovars isolated from rats in the Philippines. Microbiology (2014). (2014); 160; 418–428
  • Satoshi M, Mitsumasa S, Takaaki K, Villanueva SYAMV, Gloriani NG and Yoshida S.. Destruction of the hepatocyte junction by intercellular invasion of Leptospira causes jaundice in a hamster model of Weil’s disease.. Int. J. Exp. Path. (2014). (2014); 95; 271-281
  • Saito M, Villanueva SYAM, Kawamura Y, Iida K, Tomida J, Kanemaru T, Kohno E, Miyahara S, Umeda A, Amako K, Gloriani NG and Yoshida S.. Leptospira idonii sp, nov. isolated from environmental water.. International J of Systematic and Evolutionary Microbiology (2013). (2013); 63; 2457-2462
  • Gloriani, N.G., Cavinta, L.L., Baterna, R.A., Estrada, C.A.M., Rivera, A.K.B., Yoshida, S.I., Villanueva, S.Y.A.M. & Yanagihara, Y., . Challenges in the Development of Vaccines for Leptospirosis in the Philippines (Conference Proceedings). Journal of Vaccines & Vaccination. (2011); 2 (5);
  • Villanueva SYAM, Baterna RA, Cavinta LL, Yanagihara Y, Gloriani NG, Yoshida S. Seroprevalence of leptospirosis among water buffaloes, pigs, and dogs in selected areas in the Philippines, 2007 to 2008. Acta Medica Philippina (in press). ; ;
  • Tabo N, Villanueva SYAM, Gloriani N. Prevalence of Leptospira-agglutinating Antibodies in Abattoir workers and slaughtered an-imals in selected slaughterhouses in Cavite, Philippines. Philippine Journal of Science (in press). ; ;
  • Ozuru R, Saito M, Kanemaru T, Miyahara S, Villanueva SYAM, Murray GL, Adler B, Fujii J, Yoshida S. Adipose tissue is the first colonization site of Leptospira interrogans in subcutaneously infected hamsters. PLOS One. ; ;
  • Saito M, Miyahara S, Villanueva SYAM, Aramaki N, Ikejiri M, Kobayashi Y, Guevarra JP, Masuzawa T, Gloriani NG, Yanagihara Y and Yoshida S.. PCR and Culture Identification of Pathogenic Leptospira spp. from Coastal Soil in Leyte, Philippines, after a Storm Surge during Super Typhoon Haiyan (Yolanda). Appl. Environ. Microbiol. ; 80 (22); 6926