Title of Study

• Development of DNA vaccine and its evaluation
• Development of killed-vaccine and its evaluation
• Development of component vaccines and its evaluation

Team

• Project leaders
  • Dr. Shin-ichi Yoshida (KU)
  • Dr. Nina G. Gloriani
• Co-Leader
  • Prof. Lolita L. Cavinta
• Researchers and Assistants
  • Dr. Yasutake Yanagihara (US)
  • Dr. Toshiyuki Masuzawa (CIS)
  • Dr. Mitsumasa Saito(KU)
  • Ms. Rubelia Baterna
  • Ms. Crystal Amiel Estrada
  • Ms. Ana Kriselda Rivera

General Objective

Development of DNA vaccine to prevent leptospirosis in animal

Specific Objectives

To prepare killed vaccine consisting of prevalent strains

To prepare component vaccine consisting or prevalent strains

To prepare DNA vaccines which are protective against leptospirosis due to various serovars